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Drug Effects on the Thyroid

Henry B. Burch, M.D.

Abstract: The list of medications, many commonly used, that adversely affect thyroid function or the interpretation of standard thyroid tests is growing. This review addresses drug-induced thyroid dysfunction, emphasizing clinically relevant interactions and laboratory assay artifacts.

August 22, 2019
N Engl J Med 2019; 381:749-761
DOI: 10.1056/NEJMra1901214

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Author Affiliations
From the Division of Diabetes, Endocrinology, and Metabolic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD.
Address reprint requests to Dr. Burch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 6707 Democracy Blvd., Bethesda, MD 20892, or at henry.burch@nih.gov.